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Cold-turkey discontinuation may set up regain because four forces converge: appetite returns as the drug washes out, lean mass lost during the deficit is already gone, retatrutides glucagon-arm metabolic lift fades fast, and hunger-hormone defenses persist for about 12 months after major weight loss
For patients with diabetes, more frequent blood glucose monitoring helps prevent hypoglycemic episodes that could pose neurological risk
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No severe hypoglycaemic episodes were reported
Comparing integrative cognitive-affective therapy and guided self-help cognitive-behavioral therapy to treat binge-eating disorder using standard and naturalistic momentary outcome measures: a randomized controlled trial
We investigated the potential beneficial effects of the GLP-1RA semaglutide during juvenile protein malnutrition, a dietary challenge known to cause stunted growth and to disrupt metabolic homeostasis
